O-084. Sexual differentiation of the human hypothalamus
نویسندگان
چکیده
منابع مشابه
Sexual Differentiation of Neuronal Circuitry in the Neuroendocrine Hypothalamus
• Estrogen or aromatizable androgen exerts potent influences on modulating neural development and neural circuit formation in developing sex steroid-sensitive neuroendocrine hypothalamus. Sex steroids can act as a neurotropic factor on neural tissues, stimulating axonal and dendritic growth and synapse formation. Sex steroids are involved in regulation of expression of certain structural protei...
متن کامل[Sexual differentiation of the human brain].
Normal human development requires the compatibility between genetic sex (sex chromosomes), sex of gonades (tests or ovaries), genitalia (external and internal sex organs), somatic features (body characteristics) and psychic sex. The psychic sex, called frequently gender, consist of gender identity (self-estimation), gender role (objective estimation) and sexual orientation (hetero- or homosexua...
متن کاملSexual differentiation of the human brain in relation to gender identity and sexual orientation.
During the intrauterine period the fetal brain develops in the male direction through a direct action of testosterone on the developing nerve cells, or in the female direction through the absence of this hormone surge. In this way, our gender identity (the conviction of belonging to the male or female gender) and sexual orientation are programmed into our brain structures when we are still in t...
متن کاملSexual differentiation of the human brain: relevance for gender identity, transsexualism and sexual orientation.
Male sexual differentiation of the brain and behavior are thought, on the basis of experiments in rodents, to be caused by androgens, following conversion to estrogens. However, observations in human subjects with genetic and other disorders show that direct effects of testosterone on the developing fetal brain are of major importance for the development of male gender identity and male heteros...
متن کامل[Disorders of sexual differentiation and sexual development].
The determination of a baby’s sex begins at the chromosomal level with the insemination of the ovum. Further sexual differentiation follows during the subsequent embryogenesis. However, chromosomal anomalies, gene mutations, and other exogenous or endogenous factors can cause disorders of sexual differentiation. These disorders manifest during childhood or at the latest in puberty, making patie...
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ژورنال
عنوان ژورنال: Human Reproduction
سال: 1999
ISSN: 1460-2350,0268-1161
DOI: 10.1093/humrep/14.suppl_3.46